Publications

Our Journal Covers

2017

35. Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation
Cell Rep. 2017 Jan 24;18(4):831-839 
Lerit DA, Shebelut CW, Lawlor KJ, Rusan NM, Gavis ER, Schedl P, Deshpande G.

34. Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments
Nature Cell Biology, Jan 23. doi: 10.1038/ncb3463
Beach JR, Bruun KS, Shao L, Li D, Swider Z, Remmert K, Zhang Y, Conti MA,  Adelstein RS, Rusan NM, Betzig E, Hammer JA

2016

33. A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4
Nature Communications, 7:12476
Galletta BJ, Fagerstrom CJ, Schoborg TA, McLamarrah TA, Ryniawec JM, Buster DW, Slep KC, Rogers GC, Rusan NM 

32. Taking Centrioles to the Elimination Round
Originally titled – “Hey Centrioles, Mama Said Knock You Out”
Developmental Cell, 38(1):10-2
Schoborg TA, Rusan NM 

31. Asterless is required for centriole length control and sperm development
Journal of Cell Biology, 23;213(4):435-50
Galletta BJ, Jacobs KC, Fagerstrom CJ, Rusan NM 

___Selected for Cover

 

2015

30. Newly Characterized Region of CP190 Associates with Microtubules and Mediates Proper Spindle Morphology in Drosophila Stem Cells
PLoS One, 10(12):e0144174
Plevock KM, Galletta BJ, Slep KC*, Rusan NM* 
(* co-corresponding authors)

29. An Asp-CaM complex is required for Centrosome-Pole Cohesion and Centrosome Inheritance in Neural Stem Cells
Journal of Cell Biology, 211(5):987-98
Schoborg TA, Zajac AL, Fagerstrom CJ, Guillen RX, Rusan NM 

___JCB In Focus – “How the spindle keeps its focus”

28. A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling driving a catalytic cycle of βcatenin destruction
eLife, 10.7554/eLife.08022
Pronobis MI, Rusan NM, Peifer M

27. Proper symmetric and asymmetric ER partitioning requires astral microtubules.
Open Biology, 10.1098/rsob.150067
Smyth JT, Schoborg TA, Bergman ZJ, Riggs B, Rusan NM

___Selected for Cover

26. A yeast two-hybrid approach for probing protein-protein interactions at the centrosome
Methods in Cell Biology, 129:251-77
Galletta BJ, Rusan NM

25. Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function
Journal of Cell Biology, 210(1):79-97
Lerit DA, Jordan HA, Poulton JS, Fagerstrom CJ, Galletta BJ, Peifer M, Rusan NM

___– JCB Biosights – “Interphase centrosomes flare up”

 24. Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability 
Journal of Cell Biology, 16;208(4):401-14
Klebba JE#, Galletta BJ#, Nye J, Plevock KM, Buster DW, Hollingsworth NA, Slep KC, Rusan NM*, Rogers GC*.
(# co-first authors) (* co-corresponding authors)

___– JCB In This Issue – “Asterless amplifies Plk4”

23. Autoinhibition and relief mechanism for Polo-like kinase 4 
Proc Natl Acad Sci U S A, 17;112(7):E657-66
Klebba JE, Buster DW, McLamarraha TA, Rusan NM, Rogers GC

 

2014

22. Live imaging of Drosophila larval neuroblasts
Journal of Visualized Experiments. 2014 Jul 7;(89)
Lerit DA, Plevock KM, Rusan NM

21. Drosophila Pericentrin requires interaction with Calmodulin for its function at centrosomes and neuronal basal bodies, but not at sperm basal bodies 
Molecular Biology of the Cell, 2014 Sep 15;25(18):2682-94
Galletta BJ#, Guillen RX#, Fagerstrom CJ, Brownlee CW, Lerit DA, Megraw TL, Rogers GC, Rusan NM.
(# co-first authors)

___– MBoC highlights
___Selected for Cover

2013

20. Polo-like kinase 4 autodestructs by generating its Slimb-binding phosphodegron 
Current Biology. 2013 Nov 18;23(22):2255-61
Klebba JE, Buster DW, Nguyen AL, Swatkoski S, Gucek M, Rusan NM, Rogers GC.

19. PLP inhibits the activity of interphase centrosomes to ensure their proper segregation in stem cells 
Journal of Cell Biology. 2013 Sep 30;202(7):1013-22
Lerit DA, Rusan NM.

___JCB In Focus – “PLP helps the mother centrosome stay mum”

18. Organelle asymmetry for proper fitness, function, and fate 
Chromosome Research. 2013 May;21(3):271-86
Lerit DA, Smyth JT, Rusan NM.

2012

17. Two forkhead transcription factors regulate the division of cardiac progenitor cells by a Polo-dependent pathway 
Developmental Cell. 2012 Jul 17;23(1):97-111 
Ahmad SM, Tansey TR, Busser BW, Nolte MT, Jeffries N, Gisselbrecht SS, Rusan NM, Michelson AM.

16. Phosphoregulation of STIM1 leads to exclusion of the endoplasmic reticulum from the mitotic spindle
Current Biology. 2012 Aug 21;22(16):1487-93 
Smyth JT, Beg AM, Wu S, Putney JW Jr, Rusan NM.

15. Tubulin nucleotide status controls Sas-4-dependent pericentriolar material recruitment
Nature Cell Biology. 2012 Aug;14(8):865-73 
Gopalakrishnan J, Chim YC, Ha A, Basiri ML, Lerit DA, Rusan NM, Avidor-Reiss T.

 

 ——————————— Rusan Lab Genesis – February, 2011 ———————————-

2001-2011

14. Centrosome function: sometimes less is more
Traffic. 2009. 10(5):472-81
Rusan NM, Rogers GC.

13. The SCF Slimb ubiquitin ligaseregulates Plk4/Sak levels to block centriole reduplication
Journal of Cell Biology. 2009. 184(2):225-39
Rogers GC, Rusan NM, Roberts DM, Peifer M, Rogers SL

___JCB In This Issue – “Birth control for centrioles”
___Selected for Cover

12. Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting?
Journal of Cell Biology. 2008. 183(2):203-12
Rusan NM, Akong K, Peifer M

___JCB In This Issue – “APC ain’t always necessary for axons”
___Selected for Cover

11. Original CIN: reviewing roles for APC in chromosome instability.
Journal of Cell Biology. 2008. 181(5):719-26
Rusan NM, Peifer M

10. A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells
Molecular Biology of the Cell. 2008. 19(7):3163-78
Rogers GC, Rusan NM, Peifer M, Rogers SL

___MBoC INCYTES
___Selected for Cover

9. A role for a novel centrosome cycle in asymmetric cell division
Journal of Cell Biology. 2007. 177(1):13-20
Rusan NM, Peifer M.

___– JCB In This Issue – “Centriolar inequality”
___Selected for Cover

8. SV40 VP2 and VP3 insertion into ER membranes is controlled by the capsid protein VP1: implications for DNA translocation out of the ER
Molecular Cell. 2006. 24(6):955-66
Daniels R, Rusan NM, Wadsworth P, Hebert DN

7. Simian virus 40 late proteins possess lytic properties that render them capable of permeabilizing cellular membranes
Journal of Virology. 2006. 80(13):6575-87
Daniels R, Rusan NM, Wilbuer AK, Norkin LC, Wadsworth P, Hebert DN

___Selected for Cover

6. Stable expression of fluorescently tagged proteins for studies of mitosis in mammalian cells
Nature Methods. 2005. 2(12):981-7
Wadsworth P, Rusan NM, Tulu US, Fagerstrom C

5. Centrosome fragments and microtubules are transported asymmetrically away from division plane in anaphase
Journal of Cell Biology. 2005. 168(1):21-8
Rusan NM, Wadsworth P.

___JCB In This Issue – “Thinning microtubules”

4. Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells
Current Biology. 2003. 13(21):1894-9
Tulu US, Rusan NM, Wadsworth P

___Selected for Cover

3. Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport
Journal of Cell Biology. 2002. 158(6):997-1003
Rusan NM, Tulu US, Fagerstrom C, Wadsworth P

___JCB In This Issue – “Microtubules get swept up in the excitement of mitosis”
___Selected for Cover

2. Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma
Cancer Research. 2002 Jul 15;62(14):4109-14
Landen JW, Lang R, McMahon SJ, Rusan NM, Yvon AM, Adams AW, Sorcinelli MD, Campbell R, Bonaccorsi P, Ansel JC, Archer DR, Wadsworth P, Armstrong CA, Joshi HC

1. Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin
Molecular Biology of the Cell. 2001 Apr;12(4):971-80
Rusan NM, Fagerstrom CJ, Yvon AM, Wadsworth P