Forthcoming
55. Positioning Centrioles and Centrosomes
Hannaford MR* and NM Rusan*
(* co-corresponding)
Under review
54. Using Drosophila to Uncover the Role of Organismal Physiology and the Tumor-Microenvironment in Cancer
Khan C* and NM Rusan*
(* co-corresponding)
In press, Trends in Cancer
2023
53. Cep104 is a component of the centriole distal tip complex that regulates centriole growth and contributes to Drosophila spermiogenesis
Ryniawec JM#, Hannaford MR#, Zibrat ME, Fagerstrom CJ, Galletta BJ, Aguirre SE, Guice BA, Dean SM, Rusan NM*, Rogers GC*
(# co-first authors, * co-corresponding)
Current Biology. Oct 9;33(19):4202-4216.e9
52. Spd-2 gene duplication reveals cell-type-specific pericentriolar material regulation
O’Neill RS*, Sodeinde AK#, Welsh FC#, Fagerstrom CJ, Galletta BJ, Rusan NM*
(# contributed equally, * co-corresponding)
Current Biology. Jul 24;33(14):3031-3040.e6
51. The E3 Ligase Poe Promotes Pericentrin Degradation.
Galletta BJ#, Varadarajan R#, Fagerstrom CJ, Yang B, Haase KP, McJunkin K, Rusan NM
(# co-first authors)
Molecular Biology of the Cell. Aug 1;34(9):br15
2022
50. Pericentrin interacts with Kinesin-1 to drive centriole motility.
Hannaford MR, Liu R, Billington N, Swider ZT, Galletta BJ, Fagerstrom CJ, Combs C, Sellers JR, Rusan NM
Journal of Cell Biology, 221 (9)
___– Selected for Cover
49. Traip controls mushroom body size by suppressing mitotic defects
Rusan NM *
(* co-corresponding authors)
Development. 1;149(7)
2021
48. Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O’Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE
EMBO Journal. e107336
___– Selected for Cover
47. Dynamic sex chromosome expression in Drosophila male germ cells
Nature Communications. 12(1):892
2020
46. Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End
, , , , , Mahadevaraju S, Oliver B,
(* co-corresponding authors)
Development Cell. 53(1):86-101
___– Selected for Cover
45. A molecular mechanism for the procentriole recruitment of Ana2
, , , , , ,
(* co-corresponding authors)
Journal of Cell Biology, 219 (2)
2019
44. Micro-computed tomography as a platform for exploring Drosophila development
Schoborg TA, Smith SL, Smith LN, Morris HD, Rusan NM
Development, 176685
___– Selected for Cover
43. Fascetto (PRC1) Interacting Protein (FIP) Ensures Proper Cytokinesis and Ploidy
Swider ZT#, Ng RK#, Varadarajan R, Fagerstrom CJ, Rusan NM
(# co-first authors)
Molecular Biology of the Cell, 1;30(8):992-1007
___– Selected for Cover
2018
42. Bridging centrioles and PCM in proper space and time
Varadarajan R, Rusan NM
Essays in Biochemistry, 7;62(6):793-801
41. Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state.
Boese CJ, Nye J, Buster DW, McLamarrah TA, Byrnes AE, Slep KC, Rusan NM, Rogers GC
Molecular Biology of the Cell, 15;29(23):2874-2886
40. An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly.
McLamarrah TA, Buster DW, Galletta BJ, Boese CJ, Ryniawec JM, Hollingsworth NA, Byrnes AE, Brownlee CW, Slep KC, Rusan NM, Rogers GC
Journal of Cell Biology, 217(4):1217-1231
39. Same but Different – Pleiotropy in Centrosome-Related Microcephaly.
O’Neill R, Schoborg TA, Rusan NM
Molecular Biology of the Cell, 1;29(3):241-246
38. The Centrosomin CM2 Domain is a Multi-Functional Binding Domain with Distinct Cell Cycle Roles.
Citron YR, Fagerstrom CJ, Keszthelyi B, Huang B, Rusan NM, Kelly MJS, Agard DA
PloS One, 13(1):e0190530
2017
37. A centrosomal scaffold shows some self-control
Varadarajan R, Hammer JA, Rusan NM
Journal of Biological Chemistry, 15;292(50):20410
36. Stu2 uses a 15 nm parallel coiled coil for kinetochore localization and concomitant regulation of the mitotic spindle
Haase KP, Fox JC, Byrnes AE, Adikes RC, Speed SK, Haase J, Friedman B, Cook DM, Bloom K, Rusan NM, Slep KC
Molecular Biology of the Cell, 1;29(3):285-294
35. Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation
Lerit DA, Shebelut CW, Lawlor KJ, Rusan NM, Gavis ER, Schedl P, Deshpande G
Cell Reports. 18(4):831-839
___- Selected for Cover
34. Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments
Beach JR, Bruun KS, Shao L, Li D, Swider Z, Remmert K, Zhang Y, Conti MA, Adelstein RS, Rusan NM, Betzig E, Hammer JA
Nature Cell Biology, 19(2):85-93–
2016
33. A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4
Galletta BJ, Fagerstrom CJ, Schoborg TA, McLamarrah TA, Ryniawec JM, Buster DW, Slep KC, Rogers GC, Rusan NM
Nature Communications, 7:12476
32. Taking Centrioles to the Elimination Round
Originally titled – “Hey Centrioles, Mama Said Knock You Out”
Schoborg TA, Rusan NM
Developmental Cell, 38(1):10-2
31. Asterless is required for centriole length control and sperm development
Galletta BJ, Jacobs KC, Fagerstrom CJ, Rusan NM
Journal of Cell Biology, 23;213(4):435-50
___– Selected for Cover
2015
30. Newly Characterized Region of CP190 Associates with Microtubules and Mediates Proper Spindle Morphology in Drosophila Stem Cells
Plevock KM, Galletta BJ, Slep KC*, Rusan NM*
(* co-corresponding authors)
PLoS One, 10(12):e0144174
29. An Asp-CaM complex is required for Centrosome-Pole Cohesion and Centrosome Inheritance in Neural Stem Cells
Schoborg TA, Zajac AL, Fagerstrom CJ, Guillen RX, Rusan NM
Journal of Cell Biology, 211(5):987-98
___– JCB In Focus – “How the spindle keeps its focus”
28. A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling driving a catalytic cycle of βcatenin destruction
Pronobis MI, Rusan NM, Peifer M
eLife, 10.7554/eLife.08022
27. Proper symmetric and asymmetric ER partitioning requires astral microtubules.
Smyth JT, Schoborg TA, Bergman ZJ, Riggs B, Rusan NM
Open Biology, 10.1098/rsob.150067
___– Selected for Cover
26. A yeast two-hybrid approach for probing protein-protein interactions at the centrosome
Galletta BJ, Rusan NM
Methods in Cell Biology, 129:251-77
25. Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function
Lerit DA, Jordan HA, Poulton JS, Fagerstrom CJ, Galletta BJ, Peifer M, Rusan NM
Journal of Cell Biology, 210(1):79-97
___– JCB Biosights – “Interphase centrosomes flare up”
24. Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability
Klebba JE#, Galletta BJ#, Nye J, Plevock KM, Buster DW, Hollingsworth NA, Slep KC, Rusan NM*, Rogers GC*.
(# co-first authors) (* co-corresponding authors)
Journal of Cell Biology, 16;208(4):401-14
___– JCB In This Issue – “Asterless amplifies Plk4”
23. Autoinhibition and relief mechanism for Polo-like kinase 4
Klebba JE, Buster DW, McLamarraha TA, Rusan NM, Rogers GC
Proc Natl Acad Sci U S A, 17;112(7):E657-66
2014
22. Live imaging of Drosophila larval neuroblasts
Lerit DA, Plevock KM, Rusan NM
Journal of Visualized Experiments. 2014 Jul 7;(89)
21. Drosophila Pericentrin requires interaction with Calmodulin for its function at centrosomes and neuronal basal bodies, but not at sperm basal bodies
Galletta BJ#, Guillen RX#, Fagerstrom CJ, Brownlee CW, Lerit DA, Megraw TL, Rogers GC, Rusan NM.
(# co-first authors)
Molecular Biology of the Cell, 2014 Sep 15;25(18):2682-94
___– MBoC highlights
___– Selected for Cover
2013
20. Polo-like kinase 4 autodestructs by generating its Slimb-binding phosphodegron
Klebba JE, Buster DW, Nguyen AL, Swatkoski S, Gucek M, Rusan NM, Rogers GC.
Current Biology. 2013 Nov 18;23(22):2255-61
19. PLP inhibits the activity of interphase centrosomes to ensure their proper segregation in stem cells
Lerit DA, Rusan NM.
Journal of Cell Biology. 2013 Sep 30;202(7):1013-22
___– JCB In Focus – “PLP helps the mother centrosome stay mum”
18. Organelle asymmetry for proper fitness, function, and fate
Lerit DA, Smyth JT, Rusan NM.
Chromosome Research. 2013 May;21(3):271-86
2012
17. Two forkhead transcription factors regulate the division of cardiac progenitor cells by a Polo-dependent pathway
Ahmad SM, Tansey TR, Busser BW, Nolte MT, Jeffries N, Gisselbrecht SS, Rusan NM, Michelson AM.
Developmental Cell. 2012 Jul 17;23(1):97-111
16. Phosphoregulation of STIM1 leads to exclusion of the endoplasmic reticulum from the mitotic spindle
Smyth JT, Beg AM, Wu S, Putney JW Jr, Rusan NM.
Current Biology. 2012 Aug 21;22(16):1487-93
15. Tubulin nucleotide status controls Sas-4-dependent pericentriolar material recruitment
Gopalakrishnan J, Chim YC, Ha A, Basiri ML, Lerit DA, Rusan NM, Avidor-Reiss T.
Nature Cell Biology. 2012 Aug;14(8):865-73
————- Rusan Lab Genesis – February, 2011 ————
2001-2011
14. Centrosome function: sometimes less is more
Rusan NM, Rogers GC.
Traffic. 2009. 10(5):472-81
13. The SCF Slimb ubiquitin ligaseregulates Plk4/Sak levels to block centriole reduplication
Rogers GC, Rusan NM, Roberts DM, Peifer M, Rogers SL
Journal of Cell Biology. 2009. 184(2):225-39
___– JCB In This Issue – “Birth control for centrioles”
___– Selected for Cover
12. Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting?
Rusan NM, Akong K, Peifer M
Journal of Cell Biology. 2008. 183(2):203-12
___– JCB In This Issue – “APC ain’t always necessary for axons”
___– Selected for Cover
11. Original CIN: reviewing roles for APC in chromosome instability.
Rusan NM, Peifer M
Journal of Cell Biology. 2008. 181(5):719-26
10. A multicomponent assembly pathway contributes to the formation of acentrosomal microtubule arrays in interphase Drosophila cells
Rogers GC, Rusan NM, Peifer M, Rogers SL
Molecular Biology of the Cell. 2008. 19(7):3163-78
___– MBoC INCYTES
___– Selected for Cover
9. A role for a novel centrosome cycle in asymmetric cell division
Rusan NM, Peifer M.
Journal of Cell Biology. 2007. 177(1):13-20
___– JCB In This Issue – “Centriolar inequality”
___– Selected for Cover
8. SV40 VP2 and VP3 insertion into ER membranes is controlled by the capsid protein VP1: implications for DNA translocation out of the ER
Daniels R, Rusan NM, Wadsworth P, Hebert DN
Molecular Cell. 2006. 24(6):955-66
7. Simian virus 40 late proteins possess lytic properties that render them capable of permeabilizing cellular membranes
Daniels R, Rusan NM, Wilbuer AK, Norkin LC, Wadsworth P, Hebert DN
Journal of Virology. 2006. 80(13):6575-87
___– Selected for Cover
6. Stable expression of fluorescently tagged proteins for studies of mitosis in mammalian cells
Wadsworth P, Rusan NM, Tulu US, Fagerstrom C
Nature Methods. 2005. 2(12):981-7
5. Centrosome fragments and microtubules are transported asymmetrically away from division plane in anaphase
Rusan NM, Wadsworth P.
Journal of Cell Biology. 2005. 168(1):21-8
___– JCB In This Issue – “Thinning microtubules”
4. Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells
Tulu US, Rusan NM, Wadsworth P
Current Biology. 2003. 13(21):1894-9
___– Selected for Cover
3. Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport
Rusan NM, Tulu US, Fagerstrom C, Wadsworth P
Journal of Cell Biology. 2002. 158(6):997-1003
___– JCB In This Issue – “Microtubules get swept up in the excitement of mitosis”
___– Selected for Cover
2. Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma
Landen JW, Lang R, McMahon SJ, Rusan NM, Yvon AM, Adams AW, Sorcinelli MD, Campbell R, Bonaccorsi P, Ansel JC, Archer DR, Wadsworth P, Armstrong CA, Joshi HC
Cancer Research. 2002 Jul 15;62(14):4109-14
1. Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin
Rusan NM, Fagerstrom CJ, Yvon AM, Wadsworth P
Molecular Biology of the Cell. 2001 Apr;12(4):971-80